Product Name: Oxaver
Active substance: Oxandrolone
Oxandrolone is an oral anabolic steroid derived from dihydrotestosterone. It was designed for pure anabolic effect, with no significant estrogen and progestin activity. Oxandrolone is known for it's pretty mild steroid with no side effects. It is up to 6 times more anabolic than testosterone but significantly less androgenic. This drug like athletes preparing for a competition in speed and power sports where need clean water and muscle without fat.
Cachexia of various etiologies, violation of protein metabolism (after severe injury, surgery, burns, radiation therapy), chronic infectious disease with a significant loss of protein, progressive muscular dystrophy, GCS-induced myopathy, diabetic angiopathy, the need to accelerate the regeneration of fractures, injuries, slowing growth children (Turner's syndrome, pituitary dwarfism), delayed puberty (sexual infantilism), and physical development of boys; encephalopathy against alcoholic hepatitis.
Contraindications and Cautions:
Hypersensitivity, prostate cancer, breast cancer (in men), breast cancer (in women with hypercalcemia), hypercalcemia, severe liver failure, nephrosis, glomerulonephritis (nephrotic stage), pregnacy. Chronic heart failure, coronary atherosclerosis, myocardial infarction (including history), diabetes, prostatic hyperplasia, hepatic failure, renal insufficiency, during lactation (data on the penetration of the drug in breast milk is not available), advanced age. Childhood and adolescence (risk of premature closure of the epiphyseal growth zones, early puberty in boys and virilization in girls). Acceleration of epiphyseal growth of long bones may occur in children both during treatment and for 6 months after termination.
Effect on human liver marginally, despite the fact that it is 17-alpha-alkylated steroid. Studies have shown that oxandrolone at a dose of twenty mg per day, taken for twelve weeks, has no effect on the level of liver enzymes. Signs of liver damage include, first of all, dark urine, pale stools, and pain in the right upper quadrant. The drug is not converted to estrogens, as is a derivative of dihydrotestosterone. Estrogens can cause excessive fluid accumulation in the human body and gynecomastia. The drug, taken in moderate doses, has practically no effect on the level of production of its own testosterone hormone, as it does not inhibit function of the hypothalamus, pituitary gland and testicles. At high doses of oxandrolone body reduces the production of gonadotropin. Furthermore, a drug used in a dosage eighty mg per day for twelve weeks, the testosterone level decreases to the sixty-seven percent. In the absence of stimulation of Leydig cells may develop testicular atrophy. The decrease in testosterone leads to effects such as the suppression of libido, erection and flaccid. Perhaps the elimination of the side effects of the drug, subject to the inclusion in the course of gonadotropin or a joint reception with the androgen drugs. It rarely seen side effects of oxandrolone also include abdominal pain, increased blood pressure, nausea, loss of appetite and headaches. Experts note that the drug's side effects are rare, so it can be attributed to the safest steroids.
Inside, the duration of treatment depends on the therapeutic effect, as well as possible side effects. The usual adult dose - 2.5 mg 2-4 times a day. To achieve the desired result may be to increase the daily dose of 20 mg. The course of treatment - 2-4 weeks (can be completed without interruption.) The dose for children - no more than 0.25 mg / kg / day. For the treatment of Turner syndrome recommended dose - 0.05-0.125 mg / kg / day (hereinafter, when applied in combination with growth hormone). In the treatment of delayed puberty and physical development in boys - 0.1 mg / kg / day for 3-12 months.
It increases the risk of side effects of oral anticoagulants, insulin and oral hypoglycemic drugs, antiplatelet agents. Reduces the effects of growth hormone and its derivatives (accelerates the mineralization of the epiphyseal growth zones of long bones). Corticosteroids, ACTH, ISS, corticotropin, Na +-containing drugs and foods increase water retention in the body, increasing the risk of edema, increase the severity of acne. Co-administration of hepatotoxic drugs increases the risk of liver problems.
Store in a dry place protected from light, at a temperature of 15-25 ° C. Keep out of the reach and sight of children.